Tetraaminopyrimidine Sulfate in EU cosmetics: Annex III, entry 200
Tetraaminopyrimidine Sulfate: the entry states a maximum concentration of (b) 3,4 % (calculated as sulfate); its other lines add conditions, see below. Annex III, entry 200, Regulation (EC) No 1223/2009, consolidated 18 May 2026.
- Annex
- III: List of substances which cosmetic products must not contain except subject to the restrictions laid down
- Reference number
- 200
- Chemical name/INN
- 2,4,5,6-Tetraaminopyrimidine sulphate
- Name of Common Ingredients Glossary
- Tetraaminopyrimidine Sulfate
- CAS number
- 5392-28-9
- EC number
- 226-393-0
- Version
- Consolidated version of 18 May 2026
- Official source
- Regulation (EC) No 1223/2009, consolidated text
Official wording: restrictions
- Product type, body parts: (a) Hair dye substance in oxidative hair dye products | Other: (a) (c) After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 3,4 % (calculated as sulfate)
- Product type, body parts: (b) Hair dye substance in non-oxidative hair dye products | Maximum concentration in ready for use preparation: (b) 3,4 % (calculated as sulfate)
- Product type, body parts: (c) Products intended for colouring eyelashes | Other: (c) Professional use
Official wording: conditions of use and warnings
(a) To be printed on the label:
The mixing ratio.
‘ [pictogram in the official text] Hair colourants can cause severe allergic reactions.
Read and follow instructions.
This product is not intended for use on persons under the age of 16.
Temporary “black henna” tattoos may increase your risk of allergy.
Do not colour your hair if:
- you have a rash on your face or sensitive, irritated and damaged scalp,
- you have ever experienced any reaction after colouring your hair,
- you have experienced a reaction to a temporary “black henna” tattoo in the past.’
(c) As from 3 March 2018, to be printed on the label:
‘ [pictogram in the official text] This product can cause severe allergic reactions. Read and follow instructions.
This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase the risk of allergy.
Eyelashes shall not be coloured if the consumer:
- has a rash on the face or sensitive, irritated and damaged scalp,
- has experienced any reaction after colouring hair or eyelashes,
- has experienced a reaction to a temporary “black henna” tattoo in the past.
For professional use only.
Rinse eyes immediately if product comes into contact with them’.
Want the limits by product type?
If we publish the entries grouped by product type (shampoo, sunscreen, toothpaste), we write to you once. We use the email for nothing else.